eviQ – content author – Nursing/Haematology & BMT – Full-time permanent
The Cancer Institute NSW St Leonards
For full details click here
The below roles are currently being advertised.
Cell Therapies Clinical Quality Manager
Clinical Nurse Consultant - Apheresis
Nurse Practitioner / Transitional Nurse Practitioner – BTCT
Clinical Coordinator - BTCT
An exciting opportunity exists for an enthusiastic and highly experienced Haematology/ Oncology / General Medicine Registered Nurse to join the team at Northern Health. This role requires a driven nurse leader committed to the provision of outstanding cancer care delivery and outcomes for the people and communities in the outer northern suburbs and surrounding regional communities. In the first instance this role is a full time position at 80 hours per fortnight.
For more information click here
This position closes on 31 May 2021
An opportunity currently exists for an enthusiastic and highly experienced clinical nurse leader for the role of Nurse Unit Manager - Ward 7 South, a dynamic and specialised Haematology and Bone Marrow Transplant ward.
Employment Status: Permanent Full Time
Location: Austin Hospital, Heidelberg, Victoria
Hours per week: 40
The role is a permanent full time position, located within comprehensive Cancer Services at the Olivia Newton-John Cancer Wellness & Research Centre, at the Austin Hospital.
For further information and to apply, visit the Austin Health Careers website.
Closing date: 30 May 2021
Contact Person 1: Belinda Rickard Email:
Contact Number: 0412-129-320
Contact Person 2: Helen Longton Email:
Contact Number: (61 3) 9496-9746
Monash Health are now looking to appoint an experienced nursing professional to the role of Haematology Clinical Nurse Consultant (Haematology Inpatient and Outpatients). This is a permanent (ongoing) role, working full time hours and is based at Monash Medical Centre, Clayton.
About the role
Through building and developing close working relationships with ward based medical, nursing and allied health teams, the Haematology Clinical Nurse Consultant supports and educates haematology patients and their carers from diagnosis and throughout their disease journey. This occurs in both the inpatient and outpatient settings.
Key responsibilities of the role include:
To view the full position description and to APPLY NOW, click here
Clinical Nurse Consultant - Bone Marrow Transplant Coordinator
Haematology Nurses - an exciting opportunity to join the Royal North Shore Hospital (RNSH) Transplant team in the role of Bone Marrow Transplant (BMT) Coordinator Clinical Nurse Consultant. The position is permanent full time. Closes 3 March 2021
Link to the job adv here
The HSANZ Nurses Group Myeloma Specialist Practice Network is a very active group, with Tracy King at the helm. She not only applied for and received funding from a pharma company, however, also received an Innovation Award for developing MyeTxScheduler, a tool for clinicians to create treatment schedules to help patients to adhere to treatment protocols. The tool is pre-populated with standard myeloma treatment scheduled based on eviQ protocols, with flexibility to adapt to individual patient needs.
It is being rolled out in stages across Australia and New Zealand.
More details here
President: Nicole Gavin (QLD)
Nicole Gavin is Senior Research Fellow at Queensland University of Technology and Nurse Research at the Royal Brisbane and Women’s Hospital with adjunct affiliations at the University of Queensland and Griffith University. She is an experienced haematology and bone marrow transplant nurse. Nicole’s PhD investigated the effect of parenteral nutrition on microbial growth and its influence on catheter-related infection in patients with a central venous access device. Her postdoctoral research is broadly focused in preventing and managing infections in patients diagnosed with cancer. Nicole has been an associate nurse member of HSANZ since 2010 and has been the Queensland Representative and Vice President.
Vice President – and WA rep: Andrew Steele
Andy started working in Oncology upon qualification in 1991. His first role in Haematology was 3 years later at Derriford Hospital Plymouth and he became Charge nurse there in 1998, attending the EBMT conference the same year.
In 2000 Andy moved to Kalgoorlie WA, working in Restorative and Palliative care as a manager and stayed there for 2 years before moving to Perth to work on the Haematology ward. He stayed there for 14 years night and day and then moved to the Haematology Day Ward as Clinical Nurse Specialist and then Manager in 2014. He has been a Nurses Representative for WA since 2015. He has an interest in Change theory presenting several times at the Blood conference and organised and chaired the nurses stream of Blood 2019 in Perth.
Treasurer – Elise Button
Elise Button is a Research Fellow in the Centre for Healthcare Transformation, Queensland University of Technology and Nurse Researcher in Cancer Care Services at the Royal Brisbane and Women’s Hospital. She is an experienced haematology and bone marrow transplant nurse and an early career researcher. Elise’s research interests are focused on integration of palliative care, quality measures of end-of-life care and value-based health care.
Qld State Representative Jodie Marsh
Jodie is a Nurse Practitioner Townsville University Hospital. She has 23 years’ experience in Cancer Nursing with the majority involved in Haematology, Blood and Marrow Transplant and apheresis. She is an active member of both Haematology and BMT reference group committees with EVIQ and State Wide Cancer Clinical Network Specialist Education Committee. Clinical areas of interest are Clinical Morphology, Acute Leukemias, Apheresis and Blood and Marrow Transplant. Qld Pathology credentialled in procedural Bone Marrow Biopsy.
Myeloma Specialist Practice Network - Tracy King RN MN
Tracy King is a past President of the Nurses Group and currently, Myeloma Clinical Nurse Consultant at Royal Prince Alfred Hospital; Clinical Research Fellow, Lecturer and PhD candidate at the Cancer Nursing Research Unit, Sydney University. With over 28 years’ experience in the field of Haematology / BMT, Tracy developed a specialist interest in myeloma 20yrs ago working with the International Myeloma Foundation (IMF), now Myeloma UK. Since coming to Australia Tracy has been an active member of a range of national and international professional working groups including those of the Cancer Institute NSW; Myeloma and Related Disease Registry (MRDR), Chair of the HSANZ Myeloma Specialist Practice Network (M-SPN) and Past President and co-founder of the HSANZ Nurses Group. Most recently Tracy has been invited as a member of the IMF Nurse Leadership Board (NLB) and leads the nurse’s program development and delivery during the International Myeloma Workshop (IMW). Tracy completed a master’s in nursing leadership and is currently a PhD candidate at Sydney University. She was awarded the Outstanding Research Achievement Nursing & Midwifery Award 2019 by Sydney Local Health Network (SLHD) for her leadership and research in better understanding the experiences of those affected by myeloma taking high dose steroids and the role of patient reported outcome measures (PROM).
Frailty Assessment in Multiple Myeloma
Findings from a recent inquiry
Alicia Snowden1 and Tracy King2
To download a copy of this article, click here
1Haematology Nurse Consultant, Precision Haematology, East Melbourne.
2 Myeloma Clinical Nurse Consultant | Clinical Research Fellow | PhD Candidate, Institute of Haematology, Royal Prince Alfred Hospital, Sydney.
Fit and frail are terms increasingly used in consensus guidelines for the treatment of multiple myeloma (MM). An individual patients’ fitness often informs treatment choice, dose, schedule and duration, and a range of frailty assessment tools exist to help us measure for this construct. Furthermore, we know that treatment outcomes differ between frailty groups. But what do we mean by ‘FIT’ or ‘FRAIL’, which are the best tools to measure for it, and how do/can we put frailty assessment into practice? These were the questions recently put to members of the Myeloma Specialist Practice Network (M-SPN) and the findings are presented in this short summary article.
When asked if they undertook routine frailty assessment in their MM clinical practice it became clear a range of practices and assessment types were utilised. From ‘end of the bed clinical judgements’ to formal ‘comprehensive geriatric oncology assessment (CGA),’ with most, somewhere in between.
Myeloma – the context
Myeloma is predominantly a disease of older age, with a mean age at diagnosis of 70.2 years, 40% of patients > 75 years and 26% >80 years of age (AIHW 2019). With improvements in overall survival (OS) for those with MM and an ageing of the population we expect to see more cases of MM being diagnosed each year. Myeloma commonly follows a multiply relapsing and remitting course with patients requiring successive lines of multi-drug therapy over increasing number of years. Recent approval of triplet therapy bortezomib, lenalidomide and dexamethasone (VRD) in the upfront setting for MM provides us with robust treatment approaches that aim to increase depth of response and further improve survival outcomes. The intensity of treatment needs to be balanced with ability to tolerate both predictable disease and treatment related toxicity. Incidence of toxicity may be similar between age groups, but capacity to tolerate toxicities decreases with increased age (Terpos et al 2015). Whilst transplant eligible and transplant ineligible pathways are established, optimising treatment choice should also be based on formal frailty assessment, tailoring treatment type, dose and schedule to frailty status.
What do we mean by frailty?
Frailty is a multidimensional state of diminished reserve (energy, physical ability, cognition and health) which gives rise to vulnerability and can result in reduced ability to resist stressors, including cancer and its treatment (Clegg 2013 & Rockwood 2005). Understanding the domains of vulnerability (frailty, comorbidity and disability) is essential in tailoring treatment that will optimise outcomes for individual patients.
How can we measure for frailty?
While there is no shortage of frailty tools, not all are formally validated and there appears a lack of consensus in how and when to use them. Whilst objective frailty assessment informs treatment choice, a range of other factors such as processes of care (number of hospital visits, travel, route of administration, financial concerns) and patient choice, are also taken into account.
Frailty Assessment Tools in Multiple Myeloma
IMWG Frailty Index
Activities of Daily Living (ADL)
Instrumental Activities of Daily Living (IADL)
Charlson Comorbidity Index (CCI)
MM specific tool. Incorporating assessment of comorbidities alongside daily functioning. Widely reported in MM studies, online calculator available, relatively quick.
Revised Myeloma Comorbidity Index
MM specific tool. Incorporating additional biological markers and performance measure.
Mayo Frailty Index
MM specific tool. Simple, objective tool, predicts survival independent of age and performance status.
UK Myeloma Research Alliance Risk Profile (MRP)
WHO PS (ECOG)
MM specific tool. Objective markers, quick to complete.
Comprehensive Geriatric Assessment (CGA)
Comorbidities, functional status, medications (including polypharmacy and inappropriate medication), cognition, psychological status, social support.
Generic tool, comprehensive but complex to undertake and time-consuming
ADL Activity of Daily Living, IADL Instrumental Activity of Daily Living, CCI Charlson Comorbidity Index, KPS Karnofsky Performance Status, eGFR estimated glomerular filtration rate, PFTs pulmonary function tests, ECOG-PS Eastern Cooperative Oncology Group performance status (also known as WHO PS) NT-proBNP N-terminal natriuretic peptide type B; ISS International Staging System; CRP C-reactive protein
Why should we measure for frailty?
Frailty assessment aims to identify patients with increased care needs or vulnerability that allows clinicians to individualise treatment approaches (choice of drug combination, dose and scheduling) so as to improve outcomes. The most recent Clinical Practice Guideline: Multiple Myeloma (Quach & Prince 2019), Myeloma Scientific Advisory Group (MSAG) lists frailty separately from age, comorbidities and disability, with frailty “variously defined as poor endurance, weakness and low physical activity” (p24). The guidelines provide recommendations for the assessment of suitability of elderly patients for the intensity of therapy, suggesting clinicians determine patient ‘fitness’ (fit, intermediate, frail) so as to inform treatment choice.
In the upfront setting, induction therapy followed by autologous stem cell transplant (auSCT) results in superior survival but can be hard to tolerate due to predictable treatment related toxicities, particularly in those > 70 years of age or with existing comorbidities. Furthermore, patients categorised as frail are more likely to experience grades 3-4 non-haematological toxicity of therapy, early discontinuation of treatment and a shorter OS (Palumbo et al 2015). Determining eligibility for transplant is arguably the most commonly utilised frailty assessment time point. In addition to informing transplant eligibility, frailty assessment can also inform treatment approaches, dose-attenuation and schedule changes with recommendations listed in the Clinical Practice Guideline Myeloma (Quach & Prince 2019 p24-27).
Frailty assessment in clinical practice: M-SPN members experiences
Myeloma Specialist nurses are well placed to screen for and implement frailty assessment in MM. The nurse-patient relationship can enable comprehensive patient assessment that can be hard to achieve during busy Specialist consultations. Frailty assessment and screening can provide additional information on functional or psychosocial status that may impact treatment tolerance.
The Myeloma Specialist Practice Network (M-SPN) identified variation in practice around frailty screening as a good opportunity for the group to review practices in our region. A brief email was sent out to members inquiring of their utility of frailty assessment in routine practice. Feedback was consistent across both public and private settings; while awareness of frailty measures existed, the utility of them was inconsistently applied. Approaches were admittedly ad-hoc, with medical prescriber discretion at its core. The exception was in speciality settings within MM, such as transplant centres where the Haematopoeitic Cell Transplantation – Comorbidity Index (HCT-CI) was commonly used by Transplant Nurse Coordinators pre-auSCT work-up. Other centres utilised the IMWG Frailty Index to assess newly diagnosed MM for transplant eligibility. Formal assessments using a recognised tool were also driven by study participation (e.g. ALLG/AMaRC study ‘Frail M’). The team at Barwon Health conducted a retrospective audit that looked at efficacy and safety of auSCT in elderly myeloma patients aged >65years (Er. J et al 2018). The study found the Revised Myeloma Comorbidity Index (R-MCI) tool to be useful in predicting survival in their patient population.
Other centres are incorporating systematic frailty assessment into standard MM care pathways. We identified a hospital who had embedded frailty assessment into the position description for a new MM Nurse Specialist role. They argued frailty assessment as a mechanism to identify patients at increased risk of poorer outcomes by measuring unfavourable frailty scores, optimising management of existing, undiagnosed or high risk co-morbidities, and assessing for psychosocial needs, amongst others. This is turn potentiates frailty reversibility, mitigates toxicity, prevents unplanned hospital admissions, improves therapy adherence, and enables continuation of therapy.
What are some of the challenges for frailty assessment in routine practice?
Formal assessment vs clinical judgment
Belotti and colleagues (2020) recently compared formal frailty assessment (IMWG frailty index) with clinical judgement in MM patients 65-75yrs being considered for auSCT and found similar outcomes between assessment type. This perhaps emphasises the role of clinical judgement within a multidisciplinary, patient-centred care environment as part of assessment of fitness for treatment.
Reproducibility & Reversibility
Completion of frailty assessment also involves clinical judgement, in part subjective, where assumptions can impact scoring. Robust assessment may also depend on the clinician’s experience in the care of the elderly. Factors assessed such as weakness, malnourishment, and physical endurance are modifiable especially with allied health input. Frailty scoring may therefore change over time. Furthermore, frailty scores in myeloma are commonly reported as they correlate with poor survival outcomes. Future studies could explore frailty assessment and its role in measuring ability to tolerate a treatment regimen not only for duration of therapy but its association with toxicities and impact on health-related quality of life.
Traditionally, academic conversations on frailty that explore ‘when is less more?’ are found in Palliative Care or Geriatric Journals, which silos frailty away from academic reviews on optimal treatment found in mainstream myeloma literature. The Paper by Murillo and colleagues (2018) discussing the credentials of the IMWG’s frailty score is found in the Journal of Geriatric Oncology, not in a haematology journal.
Tools are tools.
Tools exist to guide, inform, qualify, and strategize. Perhaps the lack of widespread, routine frailty assessment we found in our brief review, indicates that clinical judgement has been working to date? Assessment of suitability of elderly MM patients for intensity of therapy is complex. Whilst frailty assessment is an important component of identifying appropriate therapy for an individual patient, treatment decisions are made within a complex patient-centred paradigm, that considers a broader range of issues, not restricted to those listed within frailty tools. Furthermore, frailty assessment is a process to be undertaken over time and not only at diagnosis. Formal frailty assessment can inform treatment choice but also guide referral for assistance with modifiable health and lifestyle factors which aim to improve health, reduce frailty and possibly re-inform treatment choice.
Assessing frailty in myeloma is not a new concept, nor is there a lack of tools to do so. With an increasing number of therapies available to treat myeloma, and a treatment trajectory of successive lines of therapy over increasing number of years, continued improvements in survival will require patients to tolerate more therapies over longer periods of time. Whilst formal frailty assessment has a role in optimising intensity of therapy it can occur alongside clinical judgment within a multidisciplinary framework of patient-centred care. Frailty evolves, and so must our approach to individual assessment.
Northern Health. Victoria
Full time or part time or job-share
Download Job Adv & Job Description
An exciting opportunity exists for a Team Leader and Senior Clinical Trials Coordinator (Registered Nurse) to join our Cancer Services Clinical Trials team at Northern Health. We are seeking a full time employee, however, part time or job-share arrangements will be considered.
About our clinical trials unitCancer Services is a new Division at Northern Health, with a rapidly growing demand for both haematology and oncology services due to an expanding patient population and increasing workforce capabilities. Access to clinical trials for malignant haematology patients remains an important standard of care requirement and forms a critical component of Northern Health's Cancer Services growth strategy. To this end, we seek the appointment of a Team leader to manage a team of clinical trials nurses coordinating haematology and oncology trials. This full time role will also manage a small portfolio of haematology trials.
About the roleThis role will be responsible for set up, review and oversight of Northern Health Cancer Services clinical trials, mentoring of junior staff within the team and for the conduct of a small trials portfolio.
For further information, please contact:
Maria Tucker, Divisional Director, Nursing, Cancer Services 0418 568 702 Maria.email@example.com
Haematology Society of Australia and New Zealand (HSANZ)
145 Macquarie Street, Sydney NSW 2000
Tel: 02 8097 8114
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