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CAR-T Clinical / Translational PhD position - the Alfred

18 Aug 2022 9:41 AM | Valerie Orton (Administrator)

Advanced Trainee positon

Alfred Hospital Haematology service and the Australian Centre for Blood Diseases (ACBD) is looking for an enthusiastic candidate to join our clinical/translational PhD program exploring the role of CAR T-cell tracking in determining the outcomes of patients who receive this treatment both in standard practice and on our clinical trials. The hypothesis is that the kinetics of CAR T-cell expansion and their immune composition may be a key determinant in attaining and maintaining responses in patients with DLBCL, ALL and other haematologic malignancies under study at our institution. The study will involve clinical aspects of patient care through the CAR-T service, maintenance of registry, coordinating research sample collection for CAR-T patients, and developing flow cytometry panels of high sensitivity and specificity and performing the required flow cytometry analyses in conjunction with our Pathology Service. There will be a translational immune function analysis conducted in collaboration with the Immunology Department, Central Clinical School (CCS). Extensive infrastructure for molecular studies, immune assessment, flow cytometry is already established on the campus. Statistical support is also provided. 

We anticipate that this position will be supervised by Prof Con Tam (clinical), Dr Shaun Fleming (pathology) as well as a member of the Monash University Immunology Department co-located on-site. This position is suitable for a haematology trainee at completion of training or early career haematologist.

This is a unique opportunity to learn about CAR-T technology in the clinic, and to develop an exciting new avenue of research. Please contact Prof Con Tam Email  if you would like more information. Our anticipated start date is early 2023.

Con Tam

Shaun Fleming

Harshal Nandurkar


CONTACT

Haematology Society of Australia and New Zealand (HSANZ)
145 Macquarie Street, Sydney NSW 2000
Tel: 02 8097 8114


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